New OECD guidance sets out a harmonised approach for investigating how nanomaterials transform during gastrointestinal digestion. The document supports more consistent assessment of orally ingested nanomaterials and their potential impacts on human health
OECD Publishes Guidance on the Intestinal Fate of Ingested Nanomaterials
NIA Staff
1 min read
Summary
The OECD has expanded its nanomaterial testing toolbox with the publication of new guidance for investigating the intestinal fate of orally ingested nanomaterials using in vitro methods.
The document provides a harmonised framework for studying how nanomaterials behave and transform during passage through the gastrointestinal tract. Such transformations can significantly influence the properties of a material and, in turn, affect exposure, uptake and biological interactions.
The guidance forms part of the OECD's broader effort to develop testing approaches tailored to nanomaterials, recognising that their behaviour may not always be adequately captured through conventional chemical assessment methods.
